New Ways to Make and Analyze Sugars and Sugar-Containing Materials
Our group is finding new ways to make and analyze sugars and sugar-containing materials to dissect their important roles especially in defenses against disease, in plants, animals, and humans. One major long-term goal is to rationally design biomaterials and therapeutic interventions such as vaccines based on a deeper knowledge of these carbohydrate interactions. Most recently, we have created the first automated solution-phase method to readily synthesize oligosaccharides using methodologies that we are applying to other biologically active molecules. This automated method circumvents key problems encountered with the solid-phase approaches that allowed commercial automated synthesis of other biopolymers like DNA and peptides.
Distinguished Professor
Robert & Marjorie Mann Chair
Distinguished Professor
Linda & Jack Gill Chair in Biomolecular Science
Luther Dana Waterman Professor 2015-2020
James F. Jackson Professor 2014-2022
Veronica Siedle Professor of Chemistry
Associate Chair
Professor (O'Neill School of Public and Environmental Affairs),
Adjunct Professor (Chemistry)
Rudy Professor (O'Neill School of Public and Environmental Affairs)
Adjunct Professor (Chemistry)
Professor & Associate Vice President for Engagement
