Studying the Biophysical Chemistry of Infectious Disease
We are a highly collaborative, problem-oriented group that uses the tools of structural and chemical biology and biophysical chemistry to understand biological regulation at the molecular level. Current projects are focused on 1) transition metal homeostasis and resistance in microbial pathogens; 2) inorganic sulfur sensing and assimilation by the major hospital pathogen Staphylococcus aureus, and 3) RNA structure and protein-RNA interactions in SARS (severe acute respiratory syndrome)-related coronaviruses. Biomolecular NMR spectroscopy to understand the structure and dynamics of proteins and RNAs figures prominently in our research.
Trevor Douglas
Earl Blough Professor of Chemistry
Chemical Biology, Inorganic, Materials
Caroline Chick Jarrold
Class of 1948 Herman B Wells Endowed Professor
Adjunct Professor, Physics
Martin F. Jarrold
Distinguished Professor and Robert & Marjorie Mann Chair
Nicola L. B. Pohl
Professor and Joan & Marvin Carmack Chair, Associate Dean of Natural and Mathematical Sciences
