Studying the Biophysical Chemistry of Infectious Disease
We are a highly collaborative, problem-oriented group that uses the tools of structural and chemical biology and biophysical chemistry to understand biological regulation at the molecular level. Current projects are focused on 1) transition metal homeostasis and resistance in microbial pathogens; 2) inorganic sulfur sensing and assimilation by the major hospital pathogen Staphylococcus aureus, and 3) RNA structure and protein-RNA interactions in SARS (severe acute respiratory syndrome)-related coronaviruses. Biomolecular NMR spectroscopy to understand the structure and dynamics of proteins and RNAs figures prominently in our research.
Distinguished Professor
Robert & Marjorie Mann Chair
Distinguished Professor
Linda & Jack Gill Chair in Biomolecular Science
James F. Jackson Professor of Chemistry
Class of 1948 Herman B Wells Endowed Professor
Adjunct Professor, Physics
Associate Dean of Natural and Mathematical Sciences and Research
Associate Professor (O'Neill School of Public and Environmental Affairs),
Adjunct Professor (Chemistry)
Rudy Professor (O'Neill School of Public and Environmental Affairs)
Adjunct Professor (Chemistry)
Professor & Associate Vice President for Engagement
Professor, Department of Molecular and Cellular Biochemistry
Adjunct Professor