Charactering RNA and Protein Macromolecules Using Techniques Including X-ray Crystallography to Understand Molecular Interactions
The Dann lab characterizes RNA and protein macromolecules using techniques including X-ray crystallography to understand molecular interactions at the level required to development therapeutics for human disease or in vivo biosensors for small molecules. Our research revolves around small molecule sensing by both RNAs and proteins. Specifically, we are interested in human folate trafficking as it relates to targeted drug delivery for the treatment of cancer and autoinflammatory disease as well as the development of RNA-based biosensors using naturally occurring riboswitches as scaffolds. Researchers in the lab will learn computational modeling, structural and biophysical techniques in addition to biochemistry and molecular biology in both RNA and protein systems.
David Clemmer
Distinguished Professor
Professor and Robert & Marjorie Mann Chair
Richard DiMarchi
Distinguished Professor
Linda & Jack Gill Chair in Biomolecular Science
Trevor Douglas
Earl Blough Professor of Chemistry
Chemical Biology, Inorganic, Materials
Amar Flood
James F. Jackson Professor of Chemistry
Caroline Chick Jarrold
Class of 1948 Herman B Wells Endowed Professor
Adjunct Professor, Physics
Martin F. Jarrold
Distinguished Professor and Robert & Marjorie Mann Chair
Nicola L. B. Pohl
Professor and Joan & Marvin Carmack Chair, Associate Dean of Natural and Mathematical Sciences
Jonathan Raff
Associate Professor (SPEA),
Adjunct Professor (Chemistry)
Michael VanNieuwenhze
Standiford H. Cox Professor of Chemistry
Theodore Widlanski
Professor & Associate Vice President for Engagement