Indiana University Bloomington Indiana University Bloomington IU Bloomington

Charactering RNA and Protein Macromolecules Using Techniques Including X-ray Crystallography to Understand Molecular Interactions


The Dann lab characterizes RNA and protein macromolecules using techniques including X-ray crystallography to understand molecular interactions at the level required to development therapeutics for human disease or in vivo biosensors for small molecules. Our research revolves around small molecule sensing by both RNAs and proteins. Specifically, we are interested in human folate trafficking as it relates to targeted drug delivery for the treatment of cancer and autoinflammatory disease as well as the development of RNA-based biosensors using naturally occurring riboswitches as scaffolds. Researchers in the lab will learn computational modeling, structural and biophysical techniques in addition to biochemistry and molecular biology in both RNA and protein systems.


Veronica Siedle Associate Professor

Inorganic

Energy, Synthesis, Catalysis

James F. Jackson Professor of Chemistry

Organic

Life, Synthesis, Catalysis

Distinguished Professor
Professor and Robert & Marjorie Mann Chair

Analytical, Physical

Life, Analysis

Distinguished Professor
Linda & Jack Gill Chair in Biomolecular Science

Chemical Biology

Life, Synthesis

Provost Professor of Chemistry

Physical

Life, Analysis, Origins

James F. Jackson Professor of Chemistry

Materials, Organic, Physical

Life, Synthesis, Origins

Assistant Professor
Adjunct Professor of Physics

Inorganic, Materials, Physical

Energy

Distinguished Professor and Lilly Chemistry Alumni Professor

Chemical Biology

Life

Veronica Siedle Professor of Chemistry

Inorganic

Energy, Synthesis, Catalysis

Professor
Adjunct Professor, Physics

Materials, Physical

Energy, Life

Professor
Dorothy & Edward Bair Chair

Analytical

Life, Analysis, Origins

Class of 1948 Herman B Wells Endowed Professor
Adjunct Professor, Physics
Associate Dean of Natural and Mathematical Sciences and Research

Inorganic, Materials, Physical

Energy, Catalysis

Distinguished Professor and Robert & Marjorie Mann Chair

Analytical, Materials, Physical

Analysis, Origins

Professor and Joan & Marvin Carmack Chair

Analytical, Chemical Biology, Organic

Life, Synthesis

Associate Professor (O'Neill School of Public and Environmental Affairs),
Adjunct Professor (Chemistry)

Analytical, Physical

Analysis, Origins, Catalysis

James F. Jackson Associate Professor of Chemistry

Organic

Life, Synthesis, Catalysis

Rudy Professor (O'Neill School of Public and Environmental Affairs)
Adjunct Professor (Chemistry)

Physical

Department Chair and Professor

Materials, Physical

Energy, Origins, Catalysis

Distinguished Professor and Harry G. Day Chair

Organic

Life, Synthesis

Professor, Department of Molecular and Cellular Biochemistry
Adjunct Professor

Chemical Biology

Life