Charactering RNA and Protein Macromolecules Using Techniques Including X-ray Crystallography to Understand Molecular Interactions
The Dann lab characterizes RNA and protein macromolecules using techniques including X-ray crystallography to understand molecular interactions at the level required to development therapeutics for human disease or in vivo biosensors for small molecules. Our research revolves around small molecule sensing by both RNAs and proteins. Specifically, we are interested in human folate trafficking as it relates to targeted drug delivery for the treatment of cancer and autoinflammatory disease as well as the development of RNA-based biosensors using naturally occurring riboswitches as scaffolds. Researchers in the lab will learn computational modeling, structural and biophysical techniques in addition to biochemistry and molecular biology in both RNA and protein systems.
Distinguished Professor
Robert & Marjorie Mann Chair
Distinguished Professor
Linda & Jack Gill Chair in Biomolecular Science
Luther Dana Waterman Professor 2015-2020
James F. Jackson Professor 2014-2022
Class of 1948 Herman B Wells Endowed Professor
Adjunct Professor, Physics
Associate Dean of Natural and Mathematical Sciences and Research
Associate Professor (O'Neill School of Public and Environmental Affairs),
Adjunct Professor (Chemistry)
Rudy Professor (O'Neill School of Public and Environmental Affairs)
Adjunct Professor (Chemistry)
Professor & Associate Vice President for Engagement
Professor, Department of Molecular and Cellular Biochemistry
Adjunct Professor