Advancing Biotechnology in Academic and Commercial Ventures
At Indiana University his research group has discovered a set of incretin peptides that demonstrate unprecedented activity in animal models of diabetes and obesity. The central elements to success has been the chemistry to install within single peptides simultaneous agonism at related G-protein coupled receptors, and the counter-intuitive discovery that glucagon and GIP agonism could synergize the proven efficacy of GLP-1 in the treatment of the metabolic syndrome. Drug candidates differing in biochemical character are independently being advanced clinically by three separate pharmaceutical companies.
Distinguished Professor
Professor and Robert & Marjorie Mann Chair
Distinguished Professor
Linda & Jack Gill Chair in Biomolecular Science
James F. Jackson Professor of Chemistry
Class of 1948 Herman B Wells Endowed Professor
Adjunct Professor, Physics
Associate Dean of Natural and Mathematical Sciences
Associate Professor (SPEA),
Adjunct Professor (Chemistry)
Standiford H. Cox Professor of Chemistry
Professor & Associate Vice President for Engagement
