Advancing Biotechnology in Academic and Commercial Ventures
At Indiana University his research group has discovered a set of incretin peptides that demonstrate unprecedented activity in animal models of diabetes and obesity. The central elements to success has been the chemistry to install within single peptides simultaneous agonism at related G-protein coupled receptors, and the counter-intuitive discovery that glucagon and GIP agonism could synergize the proven efficacy of GLP-1 in the treatment of the metabolic syndrome. Drug candidates differing in biochemical character are independently being advanced clinically by three separate pharmaceutical companies.
Distinguished Professor
Robert & Marjorie Mann Chair
Distinguished Professor
Linda & Jack Gill Chair in Biomolecular Science
Luther Dana Waterman Professor 2015-2020
James F. Jackson Professor 2014-2022
Class of 1948 Herman B Wells Endowed Professor
Adjunct Professor, Physics
Associate Dean of Natural and Mathematical Sciences and Research
Associate Professor (O'Neill School of Public and Environmental Affairs),
Adjunct Professor (Chemistry)
Rudy Professor (O'Neill School of Public and Environmental Affairs)
Adjunct Professor (Chemistry)
Professor & Associate Vice President for Engagement
Professor, Department of Molecular and Cellular Biochemistry
Adjunct Professor