Charles Dann III
Associate Professor and Department Chair
(812) 856-1704
Simon 305C
Charles E. Dann III was awarded a B.S., ACS, degree in chemistry from Millsaps College in Jackson, Mississippi, in 1996. He received his Ph.D. from the Department of Biophysics & Biophysical Chemistry at Johns Hopkins University School of Medicine in Baltimore, Maryland, while working in the laboratory of Daniel Leahy. In 2002, Dr. Dann was invited to continue his studies at the University of Texas Southwestern Medical Center at Dallas as a postdoctoral fellow under the supervision of Nobel Laureate Johann Deisenhofer. After a year in this position, he received the Sara and Frank McKnight Fellowship to work as an independent fellow. Dr. Dann held this position until joining the faculty in the Department of Chemistry at Indiana University in August 2008.
The research in Dr. Dann's laboratory focuses on determining atomic resolution structures of protein and protein:ligand complexes by X-ray crystallography or cryo-EM. This structural work guides biochemical experiments aimed at understanding transport and intracellular targets of potential therapeutic lead molecules. Projects in the laboratory afford the researcher opportunities to learn computational modeling, structural and biophysical techniques, as well as general biochemistry, molecular biology, and cell biology in the context of therapeutic development focused on inflammatory disease and specific cancer types.