Probe and Control Chemical Reactions in Living Cells
Cells transduce and respond to signals through cascades of chemical reactions. Far from the simple kinetic processes we learn from textbooks, these reactions in living cells are linked in complex networks and their spatial and temporal connectivity determines cell behavior. We are interested in analyzing the functional organization of chemical reactions in living cells and developing biomaterials to control cellular signal transduction. Our goal is to apply analytical, physical, and engineering tools to quantitatively study, manipulate, and modify disease processes.