Research Divisions

Studying the Structure and Function of Bacterial Proteins


The Oakley lab studies the structure and function of bacterial proteins that are important for the appropriate distribution of chromosomes into daughter cells. Their work takes advantage of structural understanding of the E. coli condensin, MukB, to dissect its role, along with other cellular factors, in organizing bacterial chromosomes during all phases of the cell cycle. This work combines biochemical, biophysical, and microbial cell biology techniques to address this important but unsolved biological problem.