Mass Spectrometry

The MSF is located in A411 and is staffed from 9:30 to 5:30 daily and facility houses the following equipment: One Thermo MAT-95 XP magnetic sector mass spectrometer (EI and CI sources available, staff use only), two Waters LCT Classic electrospray/time-of-flight LC-MS systems (available for walk-up use), one Bruker Biflex III MALDI-TOF instrument (available for walk-up use), one Agilent 6890/5973 GC-MS (available for walk-up use), and one soon to be installed Agilent 1200/6310 ESI-quadrupole LC-MS system (available for walk-up use). See Dr. Jonathan Karty (facility manager) or Angela Hansen (Senior Mass Spectroscopist) for more information or to schedule training. Rates for IU faculty research groups can be found on the Instrumentation page of the MSF website.
Services provided:

  • Walk-up electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for both small molecules and biological samples
  • Training for the IU community in the theory and practice of modern mass spectrometry
  • High resolution, high accuracy (±5 parts per million, ppm) mass spectrometry of small molecules by electron impact, chemical ionization, and electrospray ionization
  • High mass resolution, high mass accuracy gas chromatographic mass spectrometry
  • Low mass resolution gas chromatographic mass spectrometry with both electron impact and chemical ionization sources
  • Capillary-scale (minimum column i.d. = 0.3 mm) high performance liquid chromatographic mass spectrometry (HPLC-MS) with simultaneous detection of up to two UV-VIS wavelengths
  • Analysis of air and water sensitive compounds by electron impact, chemical ionization, fast atom bombardment, electrospray ionization, and matrix assisted laser desorption/ionization.