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‘Waltzing’ nanoparticles could advance search for more effective drug delivery methods


November 16, 2018

Yan Yu Lab researchers have discovered that drug-delivering nanoparticles attach to their targets differently based upon their position when they meet — like ballroom dancers who change their moves with the music.

The study, published today in the journal ACS Nano, is significant since the “movement” of therapeutic particles when they bind to receptor sites on human cells could indicate the effectiveness of drug treatments. The effectiveness of immunotherapy, which uses the body’s own immune system to fight diseases such as cancer, depends in part upon the ability to “tune” the strength of cellular bonds, for example.

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