Department of Chemistry, has been chosen by the Indian Institute of Technology, Madras (IIT Madras, his alma mater) to receive a “Distinguished Alumnus Award” for 2014. The Award is very prestigious and given for outstanding achievements. It is particularly special for someone with a Science background since most of the Awards are usually related to Engineering/Technology achievements. The Award will be conferred during the “Distinguished Alumnus Award Function” to be held as part of the “Institute Day” at IIT Madras on April 17, 2014. (Posted 2/6/14)
Robert H. Crabtree,
Whitehead Professor and Siedle Distinguished Lecturer, will be speaking here in C122 at 4:00 pm on April 16th.
At Yale since 1977, Robert H. Crabtree is now Whitehead Professor. He has been ACS and RSC organometallic chemistry awardee, Baylor Medallist, Mond lecturer, Kosolapoff awardee, Stauffer Lecturer, has chaired the ACS Inorganic Division and is the author of an organometallic textbook. Early work on catalytic alkane C-H activation and functionalization was followed by work on H2 complexes, dihydrogen bonding, and catalysis for green and energy chemistry. He is an ACS Fellow and a Fellow of the American Academy of Arts & Sciences. (Posted 2/5/14)
Professor Silas Cook
Recipient of a 2013 Eli Lilly Grantee Award
Professor Silas Cook has been selected to receive a 2013 Eli Lilly Grantee Award. This program, the oldest research grant program in the pharmaceutical industry, is used to recognize emerging leaders in organic chemistry. Silas will receive a 2-year unrestricted research grant for $100,000. Past winners among the IU chemistry faculty include Paul Grieco, William Roush, P. Andrew Evans and Jeff Johnston. (Posted 1/22/14)
Professor Yan Yu
and graduate student Yuan Gao have uncovered how surface presentation of ligands dictates the entry of particles into immune cells, by using Janus particles that are engineered to be functionally asymmetric. The research is recently published in JACS.
Prof. Michael VanNieuwenhze
along with graduate students Erkin Kuru and Eddie Hall, postdoctoral researcher Alvin Kalinda, and collaborator Yves Brun (Department of Biology) are coauthors on two papers, which recently appeared in Nature Communications and Nature that demonstrate, for the first time, the existence of peptidoglycan in the infamous pathogen Chlamydia. Chlamydia is the cause of 1 in 10 cases of pneumonia in children and 212 million cases of the blindness-causing disease, trachoma. It was known that Chlamydia possessed the biosynthetic machinery to synthesize peptidoglycan and that they are sensitive to antibiotics (e.g.; the beta-lactams) that inhibit peptidoglycan biosynthesis. However, because Chlamydia is an obligate intracellular pathogen, the existence of peptidoglycan had never been unequivocally demonstrated (hence, the ‘Chlamydial anomaly’). The FDAA and dipeptide probes, developed by the VanNieuwenhze and Brun laboratories, were used to visualize the biosynthesis of peptidoglycan in Chlamydia and may provide tools for the identification of novel agents for treatment of infections due to this problematic pathogen. • IU Press Release. • NIH News article.
Perpetual oscillations in Nanoworld?
Graduate students R. Quick and A. Singharoy, in collaboration with Prof. Peter Ortoleva, have made the first discovery of autonomous structural oscillations in an isothermal, constant volume nanosystems using methods in computational chemistry. While such oscillations are forbidden in Macroworld, in Nanoworld they emerge via the interplay of random microscopic fluctuations and the topography of the free energy landscape. Fundamentals of the underlying statistical mechanics and applications to vaccines and molecular electronics are being investigated. In a National Science Foundation-supported INSPIRE project, this phenomenon is being tested experimentally in collaboration with Prof. E. Brown from Wright State University.
Prof. Richard DiMarchi
and international collaborators in Germany and China have now reported in Science Translational Medicine findings that show that a single molecule combining the properties of two endocrine hormones is an effective treatment for obesity and adult-onset or Type 2 diabetes. This new drug candidate also targets metabolic syndrome, which drives obesity associated with high blood pressure, high triglyceride levels and low HDL cholesterol, all of which increase the incidence of stroke and heart attack.
Ernest E. Campaigne Symposium on Heterocyclic Chemistry
Indiana University announces the Ernest E. Campaigne Symposium on Heterocyclic Chemistry was held Saturday, October 26, 2013. Thank you to all participants.
Prof. Ken Caulton
has been named recipient of the 2014 ACS Award In Organometallic Chemistry sponsored by the Dow Chemical Company Foundation. More...
Prof. Sara Skrabalak
has been named recipient of the 2014 ACS Award in Pure Chemistry sponsored by Alpha Chi Sigma Fraternity and Alpha Chi Sigma Educational Foundation. More...
Indiana University SACNAS Chapter awarded the 2013 Graduate Chapter of the Year!
Awards were announced at the Chapter Recognition Reception on Oct. 3rd. A dinner and award ceremony were held on Oct. 5th in Seattle, WA.
Indiana University Chemistry Alumni Event
Indianapolis hosted the 246th ACS meeting at the Indianapolis Convention Center on September 8-12th. The Indiana University Department of Chemistry hosted an Indiana University Chemistry Alumni Event on September 10th at the Indiana State Museum.
Megan Thielges and Sara Skrabalak
Megan Thielges and Sara Skrabalak have been awarded the Early Career Research Award from the DOE’s Office of Science.
The effort is designed to bolster the nation's scientific workforce by providing support to exceptional researchers during the crucial early career years. Awardees were selected from a pool of 770 university- and national laboratory-based applicants. Read More...
Human folate receptor model (top) and 3 antifolate drugs
NIH Director Dr. Francis Collins discusses the human folate receptor research from the lab of Assistant Professor Charles Dann III
The lab's work, recently published in PNAS, was selected by NIH Director Dr. Francis Collins for discussion in his blog Read Dr. Collins remarks...
Professor Erin Carlson on NBC Learn
Professor Erin Carlson featured on NBC Learn: Science Behind the News
Professor Erin Carlson and her group were recently featured in a piece filmed by NBC News for their series NBC Learn: Science Behind the News. The series is done in partnership with the National Science Foundation. Click on “Science Behind the News: Drug-Resistant Bacteria" on this page for the video.
From left, Soca Wibowo, Mirage Singh and Charles Dann III
IU chemists' work will aid drug design to target cancer and inflammatory disease
Chemists at Indiana University Bloomington have produced detailed descriptions of the structure and molecular properties of human folate receptor proteins, a key development for designing new drugs that can target cancer and inflammatory diseases without serious side effects. Read More...
Amar Flood, left, and Semin Lee
IU chemists produce star-shaped macromolecule that grabs large anions.
Chemists at Indiana University Bloomington have created a symmetrical, five-sided macrocycle that is easy to synthesize and has characteristics that may help expand the molecular tool box available to researchers in biology, chemistry and materials sciences. Read More...
Professors Erin Carlson and Sara Skrabalak recently named 2013 Alfred P. Sloan Foundation Research Fellows.
The Sloan Research Fellowships seek to stimulate fundamental research by early-career scientists and scholars of outstanding promise. These two-year fellowships are awarded yearly to 126 researchers in recognition of distinguished performance and a unique potential to make substantial contributions to their field.
IU researchers uncover protein's job protecting pneumonia-causing pathogen from copper poisoning.
A team of chemists and biologists led by Indiana University chemistry professor David Giedroc has described a previously unknown function of a protein they now know is responsible for protecting a major bacterial pathogen from toxic levels of copper. Read More...
Prof. Silas Cook has been awarded a five-year NSF CAREER grant entitled "Sustainable Palladium-Catalyzed C-C Bond-Forming Reactions".
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